We should change the question and ask, can you get tired? The answer is yes, you can become fatigued after long reading sessions. If you choose to imbue your tarot cards with a humanistic personality then yes, you can also say the cards will get tired.

You will notice that if you ask the same question over and over the answers become curt. It is as if the cards are annoyed at you for asking the same question.

Have you ever asked your parents the same question again and again as a child? How did they respond after the third or fourth question? I bet they became increasingly annoyed with every question. You and the tarot cards will act the same way.